Found 23 matching trials
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
PHASE1Na-GST-1 is a protein expressed during the adult stage of the hookworm life...
Location
George Washington University Medical Faculty Associates
Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults
PHASE1Na-GST-1 is a protein expressed during the adult stage of the Necator ameri...
Location
Centre de Récherches Médicales de Lambaréné
Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection
PHASE2This study evaluates the efficacy, safety and immunogenicity of different f...
Location
George Washington University
Immune Responses in the Skin After Hookworm Infection
NAFive healthy volunteers will be repeatedly exposed to L3 Necator americanus...
Location
Leiden University Medical Center
Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana
PHASE4The Ghana study will hypothesize that both the multiple dose and single dos...
Location
Noguchi Memorial Institute for Medical Research - University of Ghana
Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae
PHASE1An experimental hookworm infection model is being developed to provide earl...
Location
George Washington University Medical Faculty Associates
Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children
PHASE1Double blind, randomized, controlled, dose-escalation Phase 1 clinical tria...
Location
Centre de Recherches Médicales de Lambaréné
Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center
NAFour healthy hookworm-naive volunteers will be exposed to 50 L3 Necator ame...
Location
Leiden University Medical Center
Desensitising Celiac Disease Patients With the Human Hookworm
PHASE1We have established that the hookworm Necator americanus (Na) dramatically ...
Location
Prince Charles Hospital
Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity
PHASE2The disappearance of intestinal parasites from humans in developed countrie...
Location
Queensland Institute of Medical Research